Formula details
Product Details
Overview
Are your valuable biological samples at risk due to brittle containers cracking under deep-freeze conditions? We engineer high-performance cryo vial packaging designed to eliminate sample loss and streamline cold-chain storage.
Key Engineering Features & Structural Advantages
Extreme Thermal Stability in Liquid Nitrogen
To withstand extreme thermal shock without structural degradation. Our containers maintain physical integrity across temperature ranges from -80°C down to -196°C. Whether utilizing a durable polycarbonate cryo box or specialized polypropylene resin, our designs prevent micro-fracturing and material fatigue.
Precision Injection Molding for Automated Systems
We utilize high-precision injection molding processes to deliver tight dimensional tolerances up to ±0.02 mm. This level of precision ensures our units sit perfectly within automated freezer racks and tower systems, eliminating mechanical jamming during high-throughput sample handling.
Advanced Sample Protection and Visual Identification
Our cryo vial box designs incorporate high-contrast alphanumeric grid indexing molded or laser-etched directly onto the box base and lid.
Clear Transparent Lids: Allow rapid visual inventory without exposing samples to ambient temperature spikes.
Integrated Drain and Air Vents: Rapidly equalize vapor pressure and ensure rapid LN2 drainage during removal, preventing liquid retention or accidental lid popping.
| Structural Feature | Technical Specification | Practical Laboratory Benefit |
|---|---|---|
| Thermal Resistance | -80°C to -196°C | Safe for LN2 liquid/vapor phase and ULT freezers |
| Molding Tolerance | Precision ±0.02 mm | Seamless fit in automated liquid nitrogen storage box systems |
| Sample Indexing | High-contrast alphanumeric grid | Rapid sample identification and zero-error tracking |
| Ventilation & Drainage | Integrated bottom/lid vents | Prevents pressure buildup and liquid retention |
| Grid Configurations | 25-place, 81-place, or 100-grid options | Fits standard 2-inch and 3-inch cryogenic storage racks |
Stackable and Space-Efficient Footprints
We standardize our freezer storage box for cryo vials with a universal 133 x 133 mm footprint. Featuring anti-slip recessed lids and reinforced base grooves,maximizing vertical capacity while preventing accidental slipping.
Material Selection & Cleanroom Standards
USP Class VI Medical-Grade Resins
- Polypropylene (PP): Exceptional chemical resistance, making it the industry standard for a durable polypropylene cryogenic storage box.
- Polyethylene (PE) & Polycarbonate: Delivers high impact resistance and structural integrity under deep-freeze conditions.
- Cyclic Olefin Copolymer (COC) & COP: Premium, high-clarity polymers offering superior moisture barrier properties and virtually zero protein binding.
Through our rigorous material selection process, we guarantee zero extractables or leachables that could alter your cell lines or reagents.
ISO-Certified Cleanroom Manufacturing
Particulate contamination during production is a major threat to high-value biobanking and cell therapy applications. We produce all cryo vial packaging inside certified ISO Class 7 and Class 8 cleanrooms.
- Strict environmental controls keep bioburden and particulates out of the molding area.
- Automated injection molding limits human contact, maintaining high purity for clinical-grade packaging.
- Every batch undergoes lot-level traceability to support complete regulatory compliance.
Autoclavable & Thermal-Shock Resistant
- Extreme Thermal Range: Safely transitions from -196°C liquid nitrogen phase storage to +121°C steam autoclave sterilization.
- Zero Distortion: Reinforced wall structures prevent warping, twisting, or lid jamming after autoclaving.
- Long-Term Reusability: Designed for extended duty cycles, lowering overall replacement costs for your facility.
Standard Technical Specifications for Cryo Vial Storage Box
| Specification | Detail |
|---|---|
| Materials | USP Class VI PP, PE, COP, COC |
| Cleanroom Standard | ISO Class 7 & Class 8 certified production |
| Precision & Tolerances | Dimensional tolerance up to ±0.02 mm |
| Temperature Resistance | -196°C to +121°C (Liquid nitrogen phase to autoclavable) |
| Footprint Dimensions | Standard 133 x 133 mm (2-inch, 3-inch, or custom heights) |
| Grid Configurations | 25-place, 81-place, and 100-place layouts |
| Vial Compatibility | Holds standard cryo vials from 0.5 mL to 5.0 mL |
| Lead Times | 7–10 days for prototype samples; 2–4 weeks for custom tooling |
Precision Engineering & Cleanroom Standards
Every cryo-safe vial storage box is molded from pure USP Class VI medical-grade resins within our ISO Class 7 and Class 8 cleanroom facilities. Tight dimensional tolerances of ±0.02 mm ensure seamless fit with automated liquid handlers, automated storage systems, and freezer racks.
Grid Options & Rapid Production
Our cryo vial packaging comes in standard 133 x 133 mm footprints, featuring popular configurations such as the 81-place cryogenic vial box and 100-grid cryo storage container. For specialized biobanking needs, we provide rapid physical prototype turnaround through our fast sampling services in 7 to 10 working days, with complete custom mold development ready in 2 to 4 weeks.
Application Scenarios Across Life Sciences
- Biotechnology & Cell Therapy: Protect high-value biological samples, stem cell cultures, and genetic material. Each cryo-safe vial storage box maintains structural integrity down to -196°C, keeping samples stable through repeated freeze-thaw cycles.
- Pharmaceutical & Bioprocessing: Rely on specialized cryo vial packaging for secure cold-chain transportation and drug substance retention. Integrate these systems into your workflow with our advanced pharmaceutical cold storage solutions designed to eliminate container failure.
- Diagnostic & Clinical Testing: Streamline handling for diagnostic reagents, serum samples, and viral media. Built specifically for high-throughput diagnostic testing applications, each cryo vial box features high-contrast alphanumeric indexing for fast visual identification.
- Biobanking & Academic Research: Optimize space in ultra-low temperature (ULT) freezers and liquid nitrogen tanks. Standardized dimensions ensure seamless compatibility with standard freezer rack systems for high-density long-term archives.
Custom OEM/ODM Development Workflow for Cryo Vial Packaging
Initial Consultation & Needs Assessment
We kick off every project with a comprehensive technical review, delivering a tailored response within 12 hours.
Requirements Analysis: We evaluate your target storage conditions (-196°C liquid nitrogen phase up to +121°C autoclaving), sample volume capacities (0.5 mL to 5.0 mL), and resin choices (USP Class VI PP, PE, COP, or COC).
System Compatibility: We align the overall footprint with standard ultra-low temperature freezer racks and automated handling equipment. For specialized container development, leverage our custom medical packaging services to streamline your production timeline.
CAD Modeling & Structural Design
Our engineering team develops detailed 3D models engineered specifically for deep-freeze environments.
Stress Relief & Wall Thickness: Uniform wall geometry eliminates stress concentrations and prevents structural warping or cracking during thermal cycling.
Grid Layout & Locking Snaps: Custom-designed grid layouts (25-place, 81-place, or 100-place) feature secure locking mechanisms that stay reliable even when handled with cryogenic gloves.
Rapid Prototyping & Physical Validation
We accelerate your validation timeline by delivering functional physical prototypes in 7–10 working days. This enables your team to verify fitment with your existing
Precision Tooling & Cleanroom Injection Molding
Upon prototype approval, we manufacture custom multi-cavity steel molds within 2 to 4 weeks.
Cleanroom Manufacturing: All molding takes place inside certified ISO Class 7 and Class 8 cleanrooms to eliminate particulate contamination.
Tight Tolerances: Advanced molding controls maintain dimensional tolerances up to ±0.02 mm, delivering consistent quality for every .
Quality Control & Full Batch Traceability
Every manufacturing lot undergoes stringent quality testing before dispatch.
Verification Protocols: Comprehensive testing includes dimensional verification, bioburden testing, and mechanical impact testing under deep-freeze conditions.
Compliance Documentation: Every order includes full batch documentation, certificates of conformance (CoC), and raw material lot traceability to support your regulatory requirements.
Frequently Asked Questions (FAQ)
Can Jiahua Package design custom grid layouts or non-standard box dimensions?
Yes. We specialize in complete OEM/ODM development for specialized cryo vial storage box requirements. Whether your lab needs custom grid layouts (such as 25, 81, or 100-place), non-standard box heights, or specialized tube alignments for robotics, our engineering team designs custom multi-cavity molds in 2 to 4 weeks with functional prototypes ready in 7 to 10 days. Explore our full line of custom vial storage boxes to see how we tailor specs to fit your automated systems.
How do your cryo storage boxes handle liquid nitrogen phase storage without cracking?
Our cryo-safe vial storage box systems are precision-molded using high-purity, virgin USP Class VI resins engineered specifically to withstand thermal shock down to -196°C.
- Pressure Control: Integrated drain and air vents allow rapid LN2 drainage and air venting, preventing liquid accumulation and dangerous pressure buildup during thawing.
- Material Resilience: Selected polycarbonate and polypropylene resins resist embrittlement, ensuring the box wall will not crack or warp during repeated immersion in liquid nitrogen tanks.
What documentation is provided with custom orders?
We back every batch of cryo vial packaging with complete regulatory and quality control documentation needed for biopharma and clinical compliance:
- Certificate of Analysis (CoA): Validates precise dimensional tolerances up to ±0.02 mm and thermal stability performance.
- Material Compliance: Declarations confirming USP Class VI medical-grade status, REACH, and RoHS standards.
- Cleanroom & Lot Traceability: Certificates documenting production inside ISO Class 7 or Class 8 cleanrooms along with full batch lot numbers for strict traceability.
Check out our FAQ resource center for additional information regarding compliance standards and custom ordering workflows.
